The effect of chlorhexidine and dimethyl sulfoxide on long-term sealing ability of two calcium silicate cements in root canal

To evaluate the long-term effect of chlorhexidine (CHX) and dimethyl sulfoxide (DMSO) on sealing ability biomineralization two different calcium silicate cements (CSC) in root canal. Sixty human third molar canals were obturated with ProRoot MTA or Biodentine. Before obturation irrigated saline (control), 2% CHX 5% DMSO. Microleakage was tested after three days six months. After additional months (12 filling) roots cut into 2 mm thick dentine discs. The discs stored artificial saliva for one year. bond strength measured push-out method, failure mode evaluated a stereomicroscope. most apical disc each tooth used Vickers hardness test. No significant differences between groups found initial microleakage. leakage increased significantly during 6-month storage all except Biodentine-CHX group Biodentine-DMSO group. DMSO irrigation time, but there no statistically difference compared to MTA-control at months’ time point. reduced MTA. With Biodentine resulted higher control Fracture analysis showed distribution fractures groups, neither nor change fracture pattern significantly. test without as final irrigant dentin than any Biodentine-group. Considering that aging surface microhardness data, it appears time-related biomineralizing does not improve dentin. pure adhesive failures both cements.